A new medical technology has been developed to measure Platelet Activation in transfusable blood products. Dynamic Light Scattering (DLS) allows simple accurate rapid measurement of MicroParticles in small samples as a measure of cell activation. This session provides a background on platelet physiology, describes the effects of platelet activation on the Platelet Concentrate Product, and the clinical benefits of transfusing Resting versus Activated platelets to hematology patients. Clinical disadvantages of activated platelet transfusion include some significant early loss of increment, greater with increasing activated transfusion number, and which result in more significant delayed effects that can be difficult to detect. The application of developments in Blood Bank Information Technology are discussed which, with Business Intelligence (BI) Analysis, support rapid identification of the reduced time-between-transfusion, and increased transfusion per patient associated with activated platelet transfusion. The value of the selective use of resting platelets with BI analysis to track improved clinical outcomes, and decreased use of a scarce product, are reviewed with the improvement in cost effectiveness.